Ebola Virus is one of the terms in medical terminology that each one of us fears. The reason is the grave danger it can do to our health while also proving fatal in some cases. Ebola virus in general terms is a member of the Filoviridae family and is a causative agent of extensive viral hemorrhagic fever. There is no particular cure for Ebola virus. The virus particularly affects the most in Africa and over the past 40 years, a severe mortality rate is noticed to link with it. The recent outbreak in West Africa resulted in over 11,000 deaths.
A Cure for the Deadly Disease – A Great Relief
While scientists over a long time were judiciously engaged in finding the cure for this dreaded virus, here’s finally a piece of good news. With the hard work and effort of various scientists coming into conglomeration, a cure for Ebola Virus is most likely to be at its successful end. Full body checkup is also recommended.
Over the last decades, medical scientists have been into great efforts for finding the cure for Ebola Virus. For the same reason, they have also been carrying out several tests and evaluations on different patients with different drugs.
The Rigorous & Effective Clinical Testings
In a test initiated in earlier years, a clinical trial was halted in which two antibody drugs were found largely effective which also resulted in the 94 percent of the total patients treated to recover. This is surely a great discovery and achievement which has set a new milestone in the path of discovering a ‘cure for Ebola Virus’
A local healthcare official declared two people in the city of Goma in the Democratic Republic of Congo, suffering from the Ebola disease and were treated with the new drug as “cured”.
These drugs were tested as a part of random clinical experiments in four cities of the DRC. The preliminary results showed that the two drugs out of the total of four drugs being tested were more effective. The two drugs namely are REGN-EB3 and mAb114. This has made the scientists to halt the trial early.
Moving Towards the Cure
The most important and crucial issue which makes the virus the most dangerous is that the medical community had no reliable way to treat people infected and suffering from Ebola until now. In such a scenario, the successful trial conducted by the researchers would be a great achievement. Even if it succeeds to treat 94 percent of patients, it in an outbreak in itself
In the current DRC Ebola outbreak, 67 percent of those infected with the virus and treated with the old drug has died. However, 94 percent of the people who were being treated with one of the new drugs has recovered successfully.
These early and great results help scientists to reach closer to the cure of the disease. The deadly disease has resulted in at least 1,900 deaths in the DRC since the outbreak which began last summer. This is surely a shocking and depressing number
The randomized clinical trial started in November and at four DRC Ebola therapy facilities had 681 individuals enrolled at the time.
Those who received one of the two more efficient medicines namely REGN-EB3 and mAb114 had a higher opportunity of survival. Also, the death rate for patients receiving REGN-EB3 was 29 percent and that for the patients treated with mAb114 was 34 percent.
For the other two old medicinal drugs, the death rate was greater. It was recorded to be 49% for ZMapp and 53% for Remdesivir.
Dr. Anthony Fauci, head of the National Institute for Allergy and Infectious Diseases (NIAID), has addressed in the report that mortality rates were even lower for the individuals who were handled and treated early. To be precise, it was 6 percent for REGN-EB3 drug and 11 percent for mAb114 drug.
How Vaccines Would Help
Additional to this, efforts to vaccinate individuals against the Ebola virus will also help the slow disease spread. Merck & Co., Inc. is a company which is already distributing a vaccine in the DRC.
It is estimated that this vaccine is effective at 97.5 percent. But the vaccine’s shortage has led health officials to consider using Johnson & Johnson’s second vaccine. The development and testing of drugs to treat and prevent Ebola will still need to proceed, even with the two fresh antibody drugs and an efficient vaccine. One reason is that the virus can mutate and become resistant to therapy with any antibody therapy. So having another option to choose from is good.
No Longer Incurable
“We will no longer claim that Ebola is incurable from now on,” Dr. Jean-Jacques Muyembe, Chief Executive Officer of the Democratic Republic of the Congo National Institute for Biomedical Research, co-sponsoring the clinical study, informed journalists last week at a telephone briefing.
Nevertheless, the epidemic continues to spread, with an average of 81 fresh instances of Ebola confirmed every week, according to the World Health Organization, the United Nations ‘ worldwide health arm, which declared the present outbreak an international emergency last month. Check “full body checkup near me”.
Stewart Schneller is a professor of chemistry and biochemistry at Auburn University in Alabama. His research group seeks drug candidates for Ebola and other viruses. On the “cure of Ebola” Virus topic, he said, “Further study of small molecule antivirals, which are more easily administered in urban and remote areas and do not require refrigeration, should be encouraged to complement antibody-based therapies,”